The Unintended Consequences of Clinical Trials Regulations

The Unintended Consequences of Planning Regulations

The Deer Hunter: the Unintended Effects of Hunting Regulations

To control the deer population, state game commissions regulate the types of deer that can be legally harvested. These regulations, however, might have an unintended effect on hunting-related accidents by changing the care hunters take when firing their rifles—a moral hazard effect—or changing the composition of hunters. Using detailed data on hunting accidents and regulations in Pennsylvania c...

Reports of unintended consequences of financial incentives to improve management of hypertension

BACKGROUND Given the increase in financial-incentive programs nationwide, many physicians and physician groups are concerned about potential unintended consequences of providing financial incentives to improve quality of care. However, few studies examine whether actual unintended consequences result from providing financial incentives to physicians. We sought to document the extent to which th...

Clinical trials in molecular imaging: the importance of following the protocol.

Nuclear medicine technologists and investigators who perform imaging procedures in clinical trials often have not received training on clinical research regulations, such as Title 21, part 312, of the Code of Federal Regulations or Good Clinical Practices. These regulations directly affect implementation of the therapeutic or imaging protocol. Lack of understanding of the regulatory expectation...

Randomised Controlled Clinical Trials – The influence of this methodology on the development of theory in Psychotherapy: Some Ruminations

The pragmatic utility, for the day-to-day practise of Psychotherapy, of having an evidence base demonstrating that as a discursive genre, it is as efficacious as medication in facilitating emotional, cognitive and behaviour change, is crucial. This comparative outcome data has been gathered using Randomised Controlled Clinical Trials (RCTs), a methodology that has established itself as ‘The Gol...